Fry the ground deer burger in a large frying pan on medium-high heat and crumble it as it fries.
When it’s done, remove any excess grease, add all but 1/4 cup of the sauce to the meat and let it simmer slowly.
Cook the lasagna noodles as instructed on the box. You can do this at the same time the meat is frying to save time.
Once the meat and noodles are done preheat the oven to 350°F.
Put the 1/4 cup of reserved sauce in the bottom of the casserole dish. Then a layer of pasta, meat sauce, and a sprinkle of mozzarella cheese. Then a layer of pasta, American cheese, meat sauce, and mozzarella. Then a layer of pasta, meat sauce, and mozzarella.
Make a tent with aluminum foil and place it over the venison lasagna. You can also spray the foil (side facing the cheese) with cooking spray to be extra sure the cheese doesn't stick to it.
Place the lasagna in the oven for 30 minutes or until the cheese is melted well.
Remove from the oven, let it cool for about 10 minutes, and serve.